Coronavirus Contains “HIV Insertions”, Stoking Fears Over Artificially Created Bioweapon

Over the past few days, the mainstream press has vigorously pushed back against a theory about the origins of the coronavirus that has now infected as many as 70,000+ people in Wuhan alone (depending on whom you believe). The theory is that China obtained the coronavirus via a Canadian research program, and started molding it into a bioweapon at the Institute of Virology in Wuhan. Politifact pointed the finger at Zero Hedge, in particular, though the story was widely shared across independent-leaning media.

The theory is that the virus, which was developed by infectious disease experts to function as a bio-weapon, originated in the Wuhan-based lab of Dr. Peng Zhou, China’s preeminent researcher of bat immune systems, specifically in how their immune systems adapt to the presence of viruses like coronavirus and other destructive viruses. Somehow, the virus escaped from the lab, and the Hunan fish market where the virus supposedly originated is merely a ruse.

Now, a respected epidemiologist who recently caught flack for claiming in a twitter threat that the virus appeared to be much more contagious than initially believed is pointing out irregularities in the virus’s genome that suggests it might have been genetically engineered for the purposes of a weapon, and not just any weapon but the deadliest one of all.

In “Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag“, Indian researchers are baffled by segments of the virus’s RNA that have no relation to other coronaviruses like SARS, and instead appear to be closer to HIV. The virus even responds to treatment by HIV medications.

For those pressed for time, here are the key findings from the paper, which first focuses on the unique nature of 2019-nCoV, and then observe four amino acid sequences in the Wuhan Coronavirus which are homologous to amino acid sequences in HIV1:

Our phylogentic tree of full-length coronaviruses suggests that 2019-nCoV is closely related to SARS CoV [Fig1].

In addition, other recent studies have linked the 2019-nCoV to SARS CoV. We therefore compared the spike glycoprotein sequences of the 2019-nCoV to that of the SARS CoV (NCBI Accession number: AY390556.1). On careful examination of the sequence alignment we found that the 2019- nCoV spike glycoprotein contains 4 insertions [Fig.2]. To further investigate if these inserts are present in any other corona virus, we performed a multiple sequence alignment of the spike glycoprotein amino acid sequences of all available coronaviruses (n=55) [refer Table S.File1] in NCBI refseq (ncbi.nlm.nih.gov) this includes one sequence of 2019-nCoV[Fig.S1]. We found that these 4 insertions [inserts 1, 2, 3 and 4] are unique to 2019-nCoV and are not present in other coronaviruses analyzed. Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses . Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses (Zhou et al., 2020).

We then translated the aligned genome and found that these inserts are present in all Wuhan 2019-nCoV viruses except the 2019-nCoV virus of Bat as a host [Fig.S4]. Intrigued by the 4 highly conserved inserts unique to 2019-nCoV we wanted to understand their origin. For this purpose, we used the 2019-nCoV local alignment with each insert as query against all virus genomes and considered hits with 100% sequence coverage. Surprisingly, each of the four inserts aligned with short segments of the Human immunodeficiency Virus-1 (HIV-1) proteins. The amino acid positions of the inserts in 2019-nCoV and the corresponding residues in HIV-1 gp120 and HIV-1 Gag are shown in Table 1.

The first 3 inserts (insert 1,2 and 3) aligned to short segments of amino acid residues in HIV-1 gp120. The insert 4 aligned to HIV-1 Gag. The insert 1 (6 amino acid residues) and insert 2 (6 amino acid residues) in the spike glycoprotein of 2019-nCoV are 100% identical to the residues mapped to HIV-1 gp120. The insert 3 (12 amino acid residues) in 2019- nCoV maps to HIV-1 gp120 with gaps [see Table 1]. The insert 4 (8 amino acid residues) maps to HIV-1 Gag with gaps.

Why do the authors think the virus may be man-made? Because when looking at the above insertions which are not present in any of the closest coronavirus families, “it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time.” Instead, they can be found in cell identification and membrane binding proteins located in the HIV genome.

Since the S protein of 2019-nCoV shares closest ancestry with SARS GZ02, the sequence coding for spike proteins of these two viruses were compared using MultiAlin software. We found four new insertions in the protein of 2019-nCoV- “GTNGTKR” (IS1), “HKNNKS” (IS2), “GDSSSG” (IS3) and “QTNSPRRA” (IS4) (Figure 2). To our surprise, these sequence insertions were not only absent in S protein of SARS but were also not observed in any other member of the Coronaviridae family (Supplementary figure). This is startling as it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time.

The insertions were observed to be present in all the genomic sequences of 2019-nCoV virus available from the recent clinical isolates. To know the source of these insertions in 2019-nCoV a local alignment was done with BLASTp using these insertions as query with all virus genome. Unexpectedly, all the insertions got aligned with Human immunodeficiency Virus-1 (HIV-1). Further analysis revealed that aligned sequences of HIV-1 with 2019-nCoV were derived from surface glycoprotein gp120 (amino acid sequence positions: 404-409, 462-467, 136-150) and from Gag protein (366-384 amino acid) (Table 1). Gag protein of HIV is involved in host membrane binding, packaging of the virus and for the formation of virus-like particles. Gp120 plays crucial role in recognizing the host cell by binding to the primary receptor CD4.This binding induces structural rearrangements in GP120, creating a high affinity binding site for a chemokine co-receptor like CXCR4 and/or CCR5.

And some visuals, which lead the paper authors to conclude that “this structural change might have also increased the range of host cells that 2019-nCoV can infect”:

3D modelling of the protein structure displayed that these insertions are present at the binding site of 2019-nCoV. Due to the presence of gp120 motifs in 2019-nCoV spike glycoprotein at its binding domain, we propose that these motif insertions could have provided an enhanced affinity towards host cell receptors. Further, this structural change might have also increased the range of host cells that 2019-nCoV can infect. To the best of our knowledge, the function of these motifs is still not clear in HIV and need to be explored. The exchange of genetic material among the viruses is well known and such critical exchange highlights the risk and the need to investigate the relations between seemingly unrelated virus families.

A good recap of the findings was provided by Dr. Feigl-Ding, who started his explanatory thread by pointing out that the transmission rate outside China has surpassed the rate inside China.

But the ‘smoking gun’ in this case are pieces of the virus’s genetic code that Indian researchers, led by Prashant Pradhan at the Indian Institute of Technology, found may have been ’embedded’ from HIV, which belongs to an entirely different family of viruses.

The punchline:

To be sure, Dr. Feigl-Ding insists that he’s not trying to promote any ‘conspiracies’ about the virus being a bioweapon developed by the Chinese, although it is difficult to find a proper name for what appears to be an artificial, weaponized virus.

Another doctor chimed in with what he thought was a solid explanation for the virus’s irregularities…

…Until he realized something disturbing.

“Scary”… but relax, it’s just another ridiculous “conspiracy.”

via zerohedge

18 comments

  1. Like I have posted before, These “viruses” are developed and “inserted” into the masses to CONTROL the population growth. Doesn’t ANYONE find it suspicious that every year that goes by, a “new strain” of some kind of viruses just seems to “pop up”, and after killing many people (especially the ELDERLY , immune depressed, and very young) the “government” miraculously comes up with yet another “vaccine” that you HAVE to purchase if you want to live.

    1. Yes and just so happens that it started in the same city where the lab is located. I said it from the start that it was put there. The first person that had the coronavirus had not even been to that market according to what I read. With as many people that live in China, I do think they have ways of eliminating the population.

      1. A Man here in California spent a Month in the part of China where this event had it’s start as his Wife was born there—6 Hospital schools in that area had been working on bio. weapons–China could lose 1/2 a Billion people and not miss them==They are , after Communists—just like the U.S.S.R. that murdered 66 Million in Their GULAG.

    2. Could this be akin to air borne chemicals sprayed over populations? Could it be like the fluoride forced into America’s water supply—a chemical Hitler used in concentration camps to keep people docile?

  2. Well, Friends & Neighbors, there ya have it. “Better Living Through ‘Modern Chemistry”! Don’t ya just love those silly-assed quaker scientists??? Get taxpayer funding to research ways for the guberment to control the masses.

  3. Harvard Scientist arrested by Department of Defense for selling Chemical Biology secrets to Wuhan University of Technology for $1.5 Million, one of the personnel he was transferring samples to is an Chinese military officer. Know how to break up some protesting in Hong Kong, just spread them down with an bio- virus, break up the party quickly…

  4. The COMMUNIST CHINESE GOVERNMENT UNLEASHED A BIOLOGICAL WEAPON inside Wuhan. The allowed People to Travel INFECTED for a WEEK no IMPOSING QUARANTINE 213 PEOPLE HAVE DIED 7,000.00 INFECTED. This VIRUS IS SPREADING RAPIDLY AROUND THE WORLD. The GLOBAL MEDIA ARE LYING AS WELL AS GOVERNMENTS OF MANY NATIONS IT IS A EVIL DIABOLICAL PLOT TO REDUCE THE POPULATION AGENDA 21. SO MANY PEOPLE ARE DECEIVED AND NAIVE BUT THERE ARE MANY WHO SEE THROUGH THIS DEMONIC DECEPTION.

  5. That this strain contains “artificial strains”, must be explained and investigated! US is doing well so far to contain, but must not be complacent, especially with a 14 day period of incubation!

  6. Get of that population control conspiracy theory no one in their right mind would risk contaminating themselves or their family members to control the population of their nation but they would as a weapon against the people of the United States.

    Yet we reward our wealthy for leaving our citizens without jobs to provide jobs for Chinese nationalists.

    I will have very little respect for any Federal politicians starting with the POTUS and then the Senators until I am living far better than I am, whining, sniveling beggars, who instead of asking the peasants for donations should be asking way more from the wealthy who actually get something in return for their donations.

    1. That POTUS is the only thing between all of us and those in the government that would destroy us. Tax the rich, tax the rich, tax the rich! It’s the only thing I hear these days. Do you not realize that less wealthy people, middle class people – do not own businesses for people to work at? What would everybody do without rich people? If you wanted more money then unfortunately it must be worked toward, the right college course, the drive and the brains to succeed. Most people dont have any of that.

  7. There is only one reason a company would develop diseases and patent them and it is not good. First off why would you bother to patent something you did not expect to make money from? Patents are also only good for so long – so the companies can recover their R & D expenses. Then everyone can make what they have. The second thing I wonder is was China planning to use this as a weapon against the world – their enemies or their own people?

  8. Pardonne moi, I meant get “off” and not “of” that population control conspiracy Theory because clearly that is pure nonsense, it was created as a viral weapon against the imperial members of the Chinese government.

  9. Latruda is for HIV prevention…………since less than 1% of US needs it, I’ll be happy to buy the stock with a prescription kicker….

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